Investigating biological activity spectrum for novel quinoline analogues.

  title={Investigating biological activity spectrum for novel quinoline analogues.},
  author={Robert Musiol and Josef Jamp{\'i}lek and Katarina Kralova and Des. R. Richardson and Danuta S Kalinowski and Barbara Podeszwa and Jacek Finster and Halina Niedbala and Anna Palka and Jaroslaw Polanski},
  journal={Bioorganic & medicinal chemistry},
  volume={15 3},
The lack of the wide spectrum of biological data is an important obstacle preventing the efficient molecular design. Quinoline derivatives are known to exhibit a variety of biological effects. In the current publication, we tested a series of novel quinoline analogues for their photosynthesis-inhibiting activity (the inhibition of photosynthetic electron transport in spinach chloroplasts (Spinacia oleracea L.) and the reduction of chlorophyll content in Chlorella vulgaris Beij.). Moreover… CONTINUE READING
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