Investigating agenesis of the corpus callosum using functional MRI: a study examining interhemispheric coordination of motor control.

@article{Lum2011InvestigatingAO,
  title={Investigating agenesis of the corpus callosum using functional MRI: a study examining interhemispheric coordination of motor control.},
  author={C Lum and Mary Pat McAndrews and Andrei I. Holodny and Kathleen A. McManus and A. Crawley and Santanu Chakraborty and David J. Mikulis},
  journal={Journal of neuroimaging : official journal of the American Society of Neuroimaging},
  year={2011},
  volume={21 1},
  pages={65-8}
}
We report fMRI findings in 3 asymptomatic cases of agenesis of the corpus callosum, the largest white matter bundle in the brain, which is responsible for interhemispheric transfer of information. Sensory information was presented to 1 hemisphere, and the patients had to generate a motor response governed by the contralateral hemisphere. Enhanced ipsilateral motor pathways have been suggested as a compensation method for people with agenesis of the corpus callosums; our functional magnetic… CONTINUE READING