Investigating a case of possible field cancerization in oral squamous cell carcinoma by the use of next-generation sequencing.

Abstract

OBJECTIVES Local recurrence and the development of second primary tumors (SPT) are important factors that can influence the survival rate of oral squamous cell carcinoma (OSCC) patients. We investigate the concept of field cancerization which proposes that normal tissue adjacent to the primary tumor harbor pre-neoplastic alterations that can lead to the… (More)
DOI: 10.1016/j.oraloncology.2017.03.018

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Cite this paper

@article{Tabatabaeifar2017InvestigatingAC, title={Investigating a case of possible field cancerization in oral squamous cell carcinoma by the use of next-generation sequencing.}, author={Siavosh Tabatabaeifar and Martin J Larsen and Stine Rosenkilde Larsen and Torben Arvid Kruse and Mads Thomassen and Jens A. S\orensen}, journal={Oral oncology}, year={2017}, volume={68}, pages={74-80} }