Investigating CD99 Expression in Leukemia Propagating Cells in Childhood T Cell Acute Lymphoblastic Leukemia

@inproceedings{Cox2016InvestigatingCE,
  title={Investigating CD99 Expression in Leukemia Propagating Cells in Childhood T Cell Acute Lymphoblastic Leukemia},
  author={Charlotte V. Cox and Paraskevi Diamanti and J Moppett and Allison Blair},
  booktitle={PloS one},
  year={2016}
}
A significant number of children with T-lineage acute lymphoblastic leukemia (T-ALL) fail to respond to therapy and experience early relapse. CD99 has been shown to be overexpressed on T-ALL cells and is considered to be a reliable detector of the disease. However, the relevance of CD99 overexpression in ALL has not been investigated in a functional context… CONTINUE READING