Investigating Aspirin and Ticagrelor for the prevention of tumour cell-induced platelet aggregation

@inproceedings{Chauhan2019InvestigatingAA,
  title={Investigating Aspirin and Ticagrelor for the prevention of tumour cell-induced platelet aggregation},
  author={Meera Chauhan},
  year={2019}
}
Background:Tumour-cell induced platelet aggregation (TCIPA) increases the metastatic potential ofcancer. Mechanisms include protection of tumour cells from immune destruction,interaction of platelet receptors with tumour ligands to facilitate adhesion, andenrichment of the tumour microenvironment, promoting extravasation andproliferation. Use of antiplatelet agents could reduce TCIPA, resulting in reducedmetastatic progression and increased patient survival. Ticagrelor, a P2Y12 antagonist, isan… Expand