Investigate Global Chromosomal Interaction by Hi-C in Human Naive CD4 T Cells.


Hi-C is a methodology developed to reveal chromosomal interactions from a genome-wide perspective. Here, we described a protocol for generating Hi-C sequencing libraries in resting and activated human naive CD4 T cells to investigate activation-induced chromatin structure re-arrangement in T cell activation followed by a section reviewing the general… (More)
DOI: 10.1007/978-1-4939-7514-3_15


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