Invertebrate cytokines. III: Invertebrate interleukin-1-like molecules stimulate phagocytosis by tunicate and echinoderm cells.

@article{Beck1993InvertebrateCI,
  title={Invertebrate cytokines. III: Invertebrate interleukin-1-like molecules stimulate phagocytosis by tunicate and echinoderm cells.},
  author={Gregory Beck and Rebbeca O'Brien and Gail S. Habicht and Dan L. Stillman and Edwin Cooper and David A. Raftos},
  journal={Cellular immunology},
  year={1993},
  volume={146 2},
  pages={284-99}
}
Phagocytosis is the predominant defense mechanism of invertebrates. Here we show that phagocytosis by echinoderm bladder amoebocytes and tunicate granular amoebocytes can be enhanced by invertebrate interleukin-1-like molecules. As little as 5 ng/ml of invertebrate interleukin-1 produced a significant stimulation of echinoderm and tunicate amoebocyte phagocytosis. Stimulation of phagocytosis by echinoderm interleukin-1-like molecules was inhibited by antisera to vertebrate interleukin-1… CONTINUE READING

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