Inversions and inverted transpositions as the basis for an almost universal "format" of genome sequences.

@article{AlbrechtBuehler2007InversionsAI,
  title={Inversions and inverted transpositions as the basis for an almost universal "format" of genome sequences.},
  author={Guenter Albrecht-Buehler},
  journal={Genomics},
  year={2007},
  volume={90 3},
  pages={297-305}
}
In genome duplexes that exceed 100 kb the frequency distributions of their trinucleotides (triplet profiles) are the same in both strands. This remarkable symmetry, sometimes called Chargaff's second parity rule, is not the result of base pairing, but can be explained as the result of countless inversions and inverted transpositions that occurred throughout evolution (G. Albrecht-Buehler, 2006, Proc. Natl. Acad. Sci. USA 103, 17828-17833). Furthermore, comparing the triplet profiles of genomes… CONTINUE READING

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