Inverse relationships between the expression of MMP-7 and MMP-11 and predictors of poor prognosis of papillary thyroid carcinoma.

@article{Ito2006InverseRB,
  title={Inverse relationships between the expression of MMP-7 and MMP-11 and predictors of poor prognosis of papillary thyroid carcinoma.},
  author={Yasuhiro Ito and Hiroshi Yoshida and Kennichi Kakudo and Yasushi Nakamura and Kanji Kuma and Akira Miyauchi},
  journal={Pathology},
  year={2006},
  volume={38 5},
  pages={421-5}
}
AIMS Matrix metalloproteinases (MMPs) have various functions that play roles in carcinoma development. In this study, we investigated the expression of two representative MMPs, MMP-7 and MMP-11, in papillary thyroid carcinomas. METHODS We immunohistochemically investigated the expression of these MMPs in 196 cases of papillary carcinoma. RESULTS A high level of MMP-7 expression was observed in 56 cases (28.3%). The expression level was significantly decreased in cases showing large tumour… CONTINUE READING

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