Inverse relationship of skeletal muscle glycogen from wild-type and genetically modified mice to their phosphorylase a activity.

@article{Schliselfeld2002InverseRO,
  title={Inverse relationship of skeletal muscle glycogen from wild-type and genetically modified mice to their phosphorylase a activity.},
  author={Louis H Schliselfeld and Moris J. Danon},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={290 2},
  pages={874-7}
}
Leg muscle was biopsied and frozen for storage at -70 degrees C. from 5 wild-type mice, two knocked out acid alpha-glucosidase (GAA) gene mice, and seven glycogen synthase plus glucose muscle transporter transgenic mice. All of the wild-type mice had very little muscle glycogen (3.58 +/- 1.67 micromols glucosyl subunits per g muscle), and 52% or more of its glycogen phosphorylase activity without AMP (69% +/- 17% glycogen phosphorylase a). In contrast the GAA knockout and transgenic mice had… CONTINUE READING
1 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…