Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease.

@article{Stern1992InverseRB,
  title={Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease.},
  author={Yaakov Stern and George E Alexander and Isak Prohovnik and Richard P. Mayeux},
  journal={Annals of neurology},
  year={1992},
  volume={32 3},
  pages={371-5}
}
A higher prevalence of dementia in individuals with fewer years of education has suggested that education may protect against Alzheimer's disease (AD). We tested whether individuals with more years of education have a more advanced AD before it is clinically evident. As a measure of pathophysiological severity, we quantified regional cerebral blood flow (rCBF), by the 133Xenon inhalation technique; a specific pattern of flow reduction in the parietotemporal cortex corresponds to AD pathology… CONTINUE READING

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