Inverse effects of lipopolysaccharides on anxiety in pregnant mice and their offspring.

Abstract

This study aimed to evaluate the effects of the bacterial lipopolysaccharide (LPS) exposure during early pregnancy on anxiety-related behaviour of both pregnant female mice and their male offspring. Pregnant NMRI mice were treated with subcutaneous injections of LPS (30, 60, 120, 240 and 480 μg/kg) on the tenth gestational day of pregnancy. Pro-inflammatory… (More)
DOI: 10.1016/j.physbeh.2014.10.016

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