Inverse effects of lipopolysaccharides on anxiety in pregnant mice and their offspring.


This study aimed to evaluate the effects of the bacterial lipopolysaccharide (LPS) exposure during early pregnancy on anxiety-related behaviour of both pregnant female mice and their male offspring. Pregnant NMRI mice were treated with subcutaneous injections of LPS (30, 60, 120, 240 and 480 μg/kg) on the tenth gestational day of pregnancy. Pro-inflammatory… (More)
DOI: 10.1016/j.physbeh.2014.10.016


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