Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis.


The expression of nm23-H1 mRNA and protein was studied in colorectal cancers by Northern blotting and immunohistochemistry. All 21 colorectal cancers studied by Northern blotting had increased levels of nm23-H1 mRNA relative to the adjacent normal colonic mucosa. Increased nm23-H1 protein expression was also observed in all 36 colorectal cancer cases… (More)
DOI: 10.1038/bjc.1993.473


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