Inverse association of H2O2-producing lactobacilli and vaginal Escherichia coli colonization in women with recurrent urinary tract infections.

@article{Gupta1998InverseAO,
  title={Inverse association of H2O2-producing lactobacilli and vaginal Escherichia coli colonization in women with recurrent urinary tract infections.},
  author={Kalpana Gupta and Ann E Stapleton and Thomas M. Hooton and Pacita L. Roberts and Cynthia L Fennell and Walter E. Stamm},
  journal={The Journal of infectious diseases},
  year={1998},
  volume={178 2},
  pages={446-50}
}
Women with recurrent urinary tract infection (UTI) often demonstrate persistent vaginal colonization with Escherichia coli. Since strains of lactobacilli that produce hydrogen peroxide inhibit the growth of E. coli, the absence of these strains may predispose to E. coli colonization and to UTI. To test this hypothesis, vaginal introital cultures were obtained from 140 women, 65 with recurrent UTI (case-patients) and 75 without (controls). Vaginal E. coli colonization was significantly more… CONTINUE READING
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