Invasive pulmonary aspergillosis with hematological malignancy caused by Aspergillus terreus and in vitro susceptibility of A. terreus isolate to micafungin.

@article{Tokimatsu2007InvasivePA,
  title={Invasive pulmonary aspergillosis with hematological malignancy caused by Aspergillus terreus and in vitro susceptibility of A. terreus isolate to micafungin.},
  author={Issei Tokimatsu and Hisako Kushima and Atsuko Iwata and Kazuhiko Hashinaga and Kenji Umeki and Minoru Ohama and Kazuhiro Kohno and Hiroshi Ishii and Kenji Kishi and Masao Ogata and Kazufumi Hiramatsu and Tetsunori Saikawa and Jun-ichi Kadota},
  journal={Internal medicine},
  year={2007},
  volume={46 11},
  pages={775-9}
}
A 35-year-old man developed invasive pulmonary aspergillosis (IPA) with severe neutropenia after umbilical cord stem cell transplantation for chronic myelogenous leukemia. Filamentous fungus isolated from his sputum was identified as Aspergillus terreus. Despite systemic amphotericin B (AMPH) administration, IPA progressed. However, intravenous administration of micafungin (MCFG) and oral itraconazole improved clinical data and symptoms, although he later died of massive hemoptysis. Examination… CONTINUE READING

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