Invasive growth of hepatic angiomyolipoma; a hitherto unreported ominous histological feature.

@article{Nonomura2006InvasiveGO,
  title={Invasive growth of hepatic angiomyolipoma; a hitherto unreported ominous histological feature.},
  author={Akitaka Nonomura and Yasunori Enomoto and Maiko Takeda and Takao Tamura and Takahiko Kasai and Toshikazu Yosikawa and H Nakamime},
  journal={Histopathology},
  year={2006},
  volume={48 7},
  pages={831-5}
}
AIMS Although histological features of hepatic angiomyolipoma (AML) are highly variable, true malignant change is extremely rare. The aim was to review the histological features of invasive growth and clinical outcomes in 39 cases of hepatic AML. METHODS AND RESULTS An invasive growth pattern into surrounding hepatic parenchyma, portal triads and/or around hepatic veins was found in 24 of 39 tumours (62%). One variant showed tumour cells replacing hepatocytes within the liver cell cords. The… CONTINUE READING
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