Invasive growth: a genetic program.

  title={Invasive growth: a genetic program.},
  author={Alessandra Gentile and Paolo Maria Comoglio},
  journal={The International journal of developmental biology},
  volume={48 5-6},
Invasive growth is defined as a complex biological program which instructs cells to dissociate, migrate, degrade the surrounding matrix, proliferate and survive. Together, these processes account for tissue morphogenesis, homeostasis and repair, and can be aberrantly implemented for cancer dissemination and metastasis. Individual aspects of this process can be controlled by many cytokines and growth factors. However, coordinated regulation of invasive growth as a whole is specifically… CONTINUE READING

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