Invasive and noninvasive methods for studying pulmonary function in mice

@article{Glaab2007InvasiveAN,
  title={Invasive and noninvasive methods for studying pulmonary function in mice},
  author={Thomas Glaab and Christian Taube and Armin Braun and Wayne Mitzner},
  journal={Respiratory Research},
  year={2007},
  volume={8},
  pages={63 - 63}
}
The widespread use of genetically altered mouse models of experimental asthma has stimulated the development of lung function techniques in vivo to characterize the functional results of genetic manipulations. Here, we describe various classical and recent methods of measuring airway responsiveness in vivo including both invasive methodologies in anesthetized, intubated mice (repetitive/non-repetitive assessment of pulmonary resistance (RL) and dynamic compliance (Cdyn); measurement of low… CONTINUE READING