Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir.

Abstract

BACKGROUND Adenovirus (ADV) infection occurs in 5-21% of allogeneic hematopoietic stem cell transplants (HSCT). Symptomatic enteritis and hemorrhagic cystitis may be encountered but are seldom fatal. In contrast, mortality rates of up to 75% are reported for adenoviral pneumonia or hepatitis. Cidofovir is currently being increasingly used for treatment of… (More)

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@article{Symeonidis2007InvasiveAI, title={Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir.}, author={Nikos Nikolaidis Charalambos Symeonidis and Aleksandra Jakubowski and Simon Pierre-Louis and David B. Jaffe and Eric G. Pamer and Kent A. Sepkowitz and Ryan O'Reilly and Georgios Papanicolaou}, journal={Transplant infectious disease : an official journal of the Transplantation Society}, year={2007}, volume={9 2}, pages={108-13} }