Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia.

  title={Invasion of respiratory epithelial cells by Burkholderia (Pseudomonas) cepacia.},
  author={Jane L. Burns and Mechthild Jonas and Emil Y. Chi and Diane K. Clark and Alexander C. Berger and Adam D. Griffith},
  journal={Infection and immunity},
  volume={64 10},
Pulmonary infections caused by Burkholderia (Pseudomonas) cepacia are an important cause of morbidity and mortality in cystic fibrosis (CF) patients. Several features suggestive of cellular invasion and intracellular sequestration of B. cepacia in CF are persistence of infection in the face of antibiotic therapy to which the organism demonstrates in vitro susceptibility and a propensity to cause bacteremic infections in patients with CF. Epithelial cell invasion was demonstrated in vitro in… CONTINUE READING

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