Invasion of endothelial cells and arthritogenic potential of endocarditis-associated Corynebacterium diphtheriae.

@article{Peixoto2014InvasionOE,
  title={Invasion of endothelial cells and arthritogenic potential of endocarditis-associated Corynebacterium diphtheriae.},
  author={Renata Stavracakis Peixoto and Gabriela Andrade Pereira and Louisy Sanches dos Santos and Cl{\'a}udio Marcos Rocha-de-Souza and D{\'e}bora Leandro Rama Gomes and Cintia Silva Dos Santos and Lucia M C Werneck and Alexandre Alves de Souza de Oliveira Dias and Raphael J{\'u}nior Hirata and P E Nagao and Ana Lu{\'i}za de Mattos-Guaraldi},
  journal={Microbiology},
  year={2014},
  volume={160 Pt 3},
  pages={537-546}
}
Although infection by Corynebacterium diphtheriae is a model of extracellular mucosal pathogenesis, different clones have been also associated with invasive infections such as sepsis, endocarditis, septic arthritis and osteomyelitis. The mechanisms that promote C. diphtheriae infection and haematogenic dissemination need further investigation. In this study we evaluated the association and invasion mechanisms with human umbilical vein endothelial cells (HUVECs) and experimental arthritis in… CONTINUE READING