Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases.

@article{Kahlert2011InvasionFE,
  title={Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases.},
  author={Christoph Kahlert and Fee Klupp and Karsten Brand and Felix Lasitschka and Sven Diederichs and Johanna Kirchberg and Nuh Rahbari and Shamik Dutta and Ulrich Bork and Johannes Fritzmann and Christoph Reissfelder and Moritz Koch and Juergen Weitz},
  journal={Cancer science},
  year={2011},
  volume={102 10},
  pages={1799-807}
}
The tumor edge of colorectal cancer and its adjacent peritumoral tissue is characterized by an invasion front-specific expression of genes that contribute to angiogenesis or epithelial-to-mesenchymal transition. Dysregulation of these genes has a strong impact on the invasion behavior of tumor cells. However, the invasion front-specific expression of microRNA (miRNA) still remains unclear. Therefore, the aim of the present study was to investigate miRNA expression patterns at the invasion front… CONTINUE READING

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