Invasion and survival strategies of Anaplasma phagocytophilum.

  title={Invasion and survival strategies of Anaplasma phagocytophilum.},
  author={Jason A Carlyon and Erol Fikrig},
  journal={Cellular microbiology},
  volume={5 11},
Anaplasma phagocytophilum is an aetiological agent of human granulocytic ehrlichiosis, an emerging tick-borne zoonosis in the United States and Europe. This obligate intracellular bacterium is unique in that it colonizes polymorphonuclear leucocytes (neutrophils). Neutrophils are key players in innate immunity. These short-lived phagocytes ingest invading microorganisms and destroy them by various means, which include fusing the bacteria-containing phagosome with acidic lysosomes as well as… CONTINUE READING

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