Invasion and growth of Plasmodium falciparum in different types of human erythrocyte.

  title={Invasion and growth of Plasmodium falciparum in different types of human erythrocyte.},
  author={Robert J. M. Wilson and Geoffrey Pasvol and David J. Weatherall},
  journal={Bulletin of the World Health Organization},
  volume={55 2-3},
The susceptibility of human red blood cells to invasion by Plasmodium falciparum was investigated in microtissue cultures with different populations of erythrocytes containing fetal haemoglobin (HbF). Preferential invasion of HbF-containing erythrocytes was observed with umbilical cord blood. The parasites showed no preference for HbF cells in blood from a subject with hereditary persistence of fetal haemoglobin (HPFH). By contrast, a significant preference for HbA-containing erythrocytes was… CONTINUE READING
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