Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium.

@article{Marra1997InvasindependentAI,
  title={Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium.},
  author={Andrea Marra and Ralph R Isberg},
  journal={Infection and immunity},
  year={1997},
  volume={65 8},
  pages={3412-21}
}
Yersinia pseudotuberculosis initiates systemic disease after translocation across the intestinal epithelium. Three Y. pseudotuberculosis factors, previously identified by their ability to promote association with cultured cells, were evaluated for their relative roles in translocation. To this end, mutants defective for invasin, YadA, or pH 6 antigen were tested for movement from the intestinal lumen into the subepithelium. Within 45 min after introduction of bacteria into the lumen, wild-type… CONTINUE READING