Invariant polymorphism in virus capsid assembly.

  title={Invariant polymorphism in virus capsid assembly.},
  author={Hung Duc Nguyen and V. Sivaprasad Reddy and Charles L. Brooks},
  journal={Journal of the American Chemical Society},
  volume={131 7},
Directed self-assembly of designed viral capsids holds significant potential for applications in materials science and medicine. However, the complexity of preparing these systems for assembly and the difficulty of quantitative experimental measurements on the assembly process have limited access to critical mechanistic questions that dictate the final product yields and isomorphic forms. Molecular simulations provide a means of elucidating self-assembly of viral proteins into icosahedral… CONTINUE READING