Intropic agents in the treatment of heart failure: Despair or hope?

Abstract

Depression of myocardial contractility plays an important role in the development of heart failure; therefore, intensive interest and passion have been generated to develop cardiotonic agents to improve the contractile function of the failing heart. Inotropic agents that increase cyclic AMP, either by increasing its synthesis or reducing its degradation… (More)
DOI: 10.1007/BF00053027

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