Introns in protein‐coding genes in Archaea

@article{Watanabe2002IntronsIP,
  title={Introns in protein‐coding genes in Archaea},
  author={Yoh-ichi Watanabe and S. Yokobori and T. Inaba and A. Yamagishi and T. Oshima and Y. Kawarabayasi and H. Kikuchi and K. Kita},
  journal={FEBS Letters},
  year={2002},
  volume={510}
}
Introns in protein‐coding genes are ubiquitous in eukaryotic cells, but pre‐mRNA splicing has yet to be reported in archaeal and its viral genomes. We present evidence of introns in genes encoding a homolog of eukaryotic Cbf5p (centromere‐binding factor 5; a subunit of a small nucleolar ribonucleoprotein) in three Archaea; Aeropyrum pernix, Sulfolobus solfataricus and Sulfolobus tokodaii. Splicing of pre‐mRNAs in vivo was demonstrated by reverse transcriptase‐mediated polymerase chain reaction… Expand
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TLDR
The immunological detection of Cbf5 protein of S. tokodaii is reported, consistent with previous reports indicating that subunit composition of the splicing endonuclease contributes to substrate specificity. Expand
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TLDR
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TLDR
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TLDR
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TLDR
An overview of recently discovered tRNA maturation pathways that require intricate processing steps to finally generate the standard tRNA from these unusual tRNA genes is given. Expand
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