Intronic sequences flanking alternatively spliced exons are conserved between human and mouse.

@article{Sorek2003IntronicSF,
  title={Intronic sequences flanking alternatively spliced exons are conserved between human and mouse.},
  author={Rotem Sorek and Gil Ast},
  journal={Genome research},
  year={2003},
  volume={13 7},
  pages={1631-7}
}
Comparison of the sequences of mouse and human genomes revealed a surprising number of nonexonic, nonexpressed conserved sequences, for which no function could be assigned. To study the possible correlation between these conserved intronic sequences and alternative splicing regulation, we developed a method to identify exons that are alternatively spliced in both human and mouse. We compiled two exon sets: one of alternatively spliced conserved exons and another of constitutively spliced… CONTINUE READING
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