Intronic sequences are involved in neural targeting of human dopamine transporter gene expression.

@article{Kouzmenko1997IntronicSA,
  title={Intronic sequences are involved in neural targeting of human dopamine transporter gene expression.},
  author={Alexander P Kouzmenko and Ananda M{\"u}ller Pereira and Bindya S Singh},
  journal={Biochemical and biophysical research communications},
  year={1997},
  volume={240 3},
  pages={807-11}
}
Dopamine transporter (DAT) plays a key role in terminating synaptic dopaminergic transmission. DAT acts exclusively on the plasma membrane of presynaptic dopaminergic neurons and DAT gene is an appropriate model for the study of dopaminergic neuron-specific regulation of gene activity. DAT represents an important target for widely used neuroleptic drugs and psychostimulants and for catecholamine-selective neurotoxins. Functional abnormalities of DAT have been implicated in diverse neurologic… CONTINUE READING

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