Intronic polyadenylation in the human glycinamide ribonucleotide formyltransferase gene.

  title={Intronic polyadenylation in the human glycinamide ribonucleotide formyltransferase gene.},
  author={Jan A. L. van Kan and Richard G. Moran},
  journal={Nucleic acids research},
  volume={25 15},
The mouse glycinamide ribonucleotide formyltransferase (GART) locus is known to produce two functional proteins, one by recognition and use of an intronic polyadenylation site and the other by downstream splicing. We now report a similar intronic polyadenylation mechanism for the human GART locus. The human GART gene has two potential polyadenylation signals within the identically located intron as that involved in intronic polyadenylation in the mouse gene. Each of the potential… CONTINUE READING
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