From the roots of cross training to the rigorous worldwide events, triathlon has become a means for physical conditioning, competition and socialization that is adaptable to everyone with a desire and commitment to participate. The novelty of athletes with limb loss competing alongside able-bodied has passed. The current expectation is that sport, including triathlon, is well within the reach of any amputee athlete with the physical ability and determination to compete. Commitment by the clinical team to the amputee athlete along with the systematic practice of prosthetic fitting, sport-specific training and accurate record keeping will not only assist today's athletes, but will establish the foundation for future amputee triathletes. This article outlines the prosthetic and training consideration for clinicians working with novice and intermediate amputee triathletes or those interested in swimming, cycling and running. In addition, prosthetic fitting and component selection and race day strategies is discussed.