• Corpus ID: 25358388

Introduction to Protein Structure Prediction

@article{Abeln2017IntroductionTP,
  title={Introduction to Protein Structure Prediction},
  author={Sanne Abeln and Jaap Heringa and K. Anton Feenstra},
  journal={arXiv: Biomolecules},
  year={2017}
}
This chapter gives a graceful introduction to problem of protein three- dimensional structure prediction, and focuses on how to make structural sense out of a single input sequence with unknown structure, the 'query' or 'target' sequence. We give an overview of the different classes of modelling techniques, notably template-based and template free. We also discuss the way in which structural predictions are validated within the global com- munity, and elaborate on the extent to which predicted… 

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