Introduction: spatial origin of murine hematopoietic stem cells.

  title={Introduction: spatial origin of murine hematopoietic stem cells.},
  author={Mervin C. Yoder},
  volume={98 1},
Hematopoiesis is the developmentally regulated and tissue-specific process of blood cell production. The predominant anatomic site of hematopoiesis changes several times during murine and human ontogeny. Blood and endothelial cells become morphologically identifiable on embryonic day 7.5 (E7.5) in the developing murine yolk sac blood islands. 1 Upon initiation of blood flow through the systemic circulation, blood island–derived progenitor cells are carried throughout the yolk sac and embryo. 2… CONTINUE READING

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