Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks

Abstract

Light is a powerful entrainer of circadian clocks in almost all eukaryotic organisms promoting synchronization of internal circadian rhythms with external environmental light-dark (LD) cycles. In mammals, the circadian system is organized in a hierarchical manner, in which a central pacemaker in the suprachiasmatic nucleus (SCN) synchronizes oscillators in… (More)
DOI: 10.1371/journal.pone.0168651

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@inproceedings{Kofuji2016IntrinsicallyPR, title={Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) Are Necessary for Light Entrainment of Peripheral Clocks}, author={Paulo Kofuji and Ludovic S. Mure and Logan J Massman and Nicole Purrier and Satchidananda Panda and William C. Engeland}, booktitle={PloS one}, year={2016} }