Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria.

@article{Lpez2010IntrinsicNO,
  title={Intrinsic nitric oxide-stimulatory activity of lipoteichoic acids from different Gram-positive bacteria.},
  author={C{\'e}sar Jim{\'e}nez L{\'o}pez and H. Farghali and Eva Kmon{\'i}{\vc}kov{\'a}},
  journal={Nitric oxide : biology and chemistry},
  year={2010},
  volume={23 4},
  pages={
          300-10
        }
}
Lipoteichoic acid (LTA) is a structural component of the cell walls of Gram-positive bacteria. Similar to lipopolysaccharide (LPS) which is expressed in Gram-negative bacteria, LTA exhibits immunostimulatory properties. Frequently observed positive response of LTA in the Limulus amebocyte lysate (LAL) assay has been interpreted as a sign of LPS contamination, raising doubts about the intrinsic immune activities of LTA. Regarding many similarities in immunobiological and physicochemical… CONTINUE READING
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