Intrinsic biological property of colloidal fullerene nanoparticles (nC60): lack of lethality after high dose exposure to human epidermal and bacterial cells.

@article{Xia2010IntrinsicBP,
  title={Intrinsic biological property of colloidal fullerene nanoparticles (nC60): lack of lethality after high dose exposure to human epidermal and bacterial cells.},
  author={Xin Rui Xia and Nancy A Monteiro-Riviere and Jim E Riviere},
  journal={Toxicology letters},
  year={2010},
  volume={197 2},
  pages={128-34}
}
Colloidal fullerene nanoparticles (nC60) were reported to be toxic to fish brains, human cells and microorganisms, while new observations suggest that the observed toxicity may be due to tetrahydrofuran (THF) solvent or its oxidative by-products in nC60 preparations. Here, we report a novel method for preparing nC60 nanoparticles that does not use THF solvent, but provides nC60 with an average particle size of 43.8 nm and a yield approximately 100 times higher than the THF method. The prepared… CONTINUE READING