Intrinsic and extrinsic factors that shape neocortical specification.

  title={Intrinsic and extrinsic factors that shape neocortical specification.},
  author={Sarah L. Pallas},
  journal={Trends in neurosciences},
  volume={24 7},
Increasing evidence points to the importance of intrinsic molecular cues in specifying the regional identity of mammalian neocortex. Few such cues, however, have been found to be restricted to individual functionally defined cortical areas before the arrival of afferent information. In contrast, thalamocortical axons are specifically targeted to individual cortical areas, raising the possibility that they can instruct some aspects of cortical areal identity. Cortical structure and function can… CONTINUE READING