Intrinsic PEEP and arterial PCO2 in stable patients with chronic obstructive pulmonary disease.

@article{Haluszka1990IntrinsicPA,
  title={Intrinsic PEEP and arterial PCO2 in stable patients with chronic obstructive pulmonary disease.},
  author={J Haluszka and Daniel Chartrand and Alejandro Grassino and Joseph Milic-Emili},
  journal={The American review of respiratory disease},
  year={1990},
  volume={141 5 Pt 1},
  pages={1194-7}
}
Dynamic pulmonary hyperinflation and intrinsic PEEP (PEEPi) are known to play an important role in causing acute respiratory failure in COPD patients. In the present study, we have explored (1) the prevalence and magnitude of PEEPi in stable COPD patients, and (2) the correlation of PEEPi with respiratory mechanics and PaCO2. In 96 stable COPD patients with varying degrees of airway obstruction, we measured pulmonary flow resistance (RL), dynamic lung compliance (CLdyn), breathing pattern… CONTINUE READING
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