Intrinsic Functional Plasticity of the Sensory-Motor Network in Patients with Cervical Spondylotic Myelopathy

@article{Zhou2015IntrinsicFP,
  title={Intrinsic Functional Plasticity of the Sensory-Motor Network in Patients with Cervical Spondylotic Myelopathy},
  author={Fuqing Zhou and Y Tan and L. Wu and Ying Zhuang and L. C. He and Hong-han Gong},
  journal={Scientific Reports},
  year={2015},
  volume={5}
}
Several neuroimaging studies have suggested brain reorganisation in patients with cervical spondylotic myelopathy (CSM); however, the changes in spontaneous neuronal activity that are associated with connectedness remain largely unknown. In this study, functional connectivity strength (FCS), a data-driven degree centrality method based on a theoretical approach, was applied for the first time to investigate changes in the sensory-motor network (SMN) at the voxel level. Comparatively, CSM not… 
Abnormal intrinsic functional activity in patients with cervical spondylotic myelopathy: a resting-state fMRI study
TLDR
Resting-state fMRI analyses reveal central functional reorganization in the brains of patients with cervical spondylotic myelopathy and provide complementary evidence of cortex reorganizations in these patients.
Sensorimotor cortex atrophy in patients with cervical spondylotic myelopathy
TLDR
It is hypothesized that CSM causes atrophy in the sensorimotor cortices, which results in functional changes during CSM progression, which provides new insights into the compensatory reaction in CSM patients.
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Objective Advanced magnetic resonance imaging studies have shown functional plasticity or reorganization and metabolite alterations of N-acetyl aspartate in the sensorimotor cortex (SMC), a hallmark
Disruption of human brain connectivity networks in patients with cervical spondylotic myelopathy.
TLDR
Altered functional topological organization in CSM patients may indicate sensory-motor dysfunction and blurred vision in patients with cervical spondylotic myelopathy, and the increased DMN may indicate increased psychological processing inCSM patients.
Functional Connectivity Changes of the Visual Cortex in the Cervical Spondylotic Myelopathy Patients: A Resting-State fMRI Study.
TLDR
FC changes were present in the visual cortex of CSM patients, which negatively correlated with preoperative JOA scores and positively correlated withPreoperative BCVA, and significant recovery of FC in theVisual cortex was detected in CSM Patients postoperatively.
Functional MRI evidence for primary motor cortex plasticity contributes to the disease’s severity and prognosis of cervical spondylotic myelopathy patients
TLDR
The functional state of M1 contributes to the disease’s severity of CSM and can provide complementary information for predicting the prognosis of CSm patients following decompression surgery, indicating cortical function contributes to disease severity ofCSM.
Abnormal intrinsic brain functional network dynamics in patients with cervical spondylotic myelopathy
TLDR
Investigating the dynamic functional connection of patients with CSM, focusing on the temporal characteristics of the functional connection state patterns and the variability of network topological organization, found that the mean dwell time in state 2 was significantly different between the two groups.
The Correlation between Functional Connectivity of the Primary Somatosensory Cortex and Cervical Spinal Cord Microstructural Injury in Patients with Cervical Spondylotic Myelopathy
TLDR
There was synchronization between chronic cervical spinal Cord microstructural injury and cerebral cortex sensory function compensatory recombination and DTI parameters of the posterior cervical spinal cord could objectively reflect the degree of cerebral cortex sensor function impairment to a certain extent.
Regional Homogeneity and Multivariate Pattern Analysis of Cervical Spondylosis Neck Pain and the Modulation Effect of Treatment
TLDR
CSNP patients are associated with dysfunction of the rTPJ and sensorimotor area, and MVPA could discriminate CSNP patients from HCs with 72% accuracy and predict clinical outcomes with a mean absolute error of 19.6%.
Amplitude of Low Frequency Fluctuation (ALFF) in the Cervical Spinal Cord with Stenosis: A Resting State fMRI Study
TLDR
Whether the level of neural activity changes on the myelopathic cervical cord is evaluated and the possible relationship between this change and clinical symptoms through amplitude of low frequency fluctuation (ALFF) is evaluated to enrich understanding on the neural development mechanism of CSM.
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