Intravitreal properties of porous silicon photonic crystals: a potential self-reporting intraocular drug-delivery vehicle.

@article{Cheng2008IntravitrealPO,
  title={Intravitreal properties of porous silicon photonic crystals: a potential self-reporting intraocular drug-delivery vehicle.},
  author={Lingyun Cheng and Emily J Anglin and Fr{\'e}d{\'e}rique Cunin and D Kim and Michael J Sailor and Iryna A Falkenstein and Ajay M Tammewar and William R. Freeman},
  journal={The British journal of ophthalmology},
  year={2008},
  volume={92 5},
  pages={705-11}
}
AIM To determine the suitability of porous silicon photonic crystals for intraocular drug-delivery. METHODS A rugate structure was electrochemically etched into a highly doped p-type silicon substrate to create a porous silicon film that was subsequently removed and ultrasonically fractured into particles. To stabilise the particles in aqueous media, the silicon particles were modified by surface alkylation (using thermal hydrosilylation) or by thermal oxidation. Unmodified particles… CONTINUE READING

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