Intravitreal pro-inflammatory cytokines in non-obese diabetic mice: Modelling signs of diabetic retinopathy

@inproceedings{Mugisho2018IntravitrealPC,
  title={Intravitreal pro-inflammatory cytokines in non-obese diabetic mice: Modelling signs of diabetic retinopathy},
  author={Odunayo O Mugisho and Ilva Dana Rupenthal and D. C. M. Squirrell and Sarah J Bould and Helen V. Danesh-Meyer and Jie Zhang and Colin Richard Green and Monica L Acosta},
  booktitle={PloS one},
  year={2018}
}
Diabetic retinopathy is a vascular disease of the retina characterised by hyperglycaemic and inflammatory processes. Most animal models of diabetic retinopathy are hyperglycaemia-only models that do not account for the significant role that inflammation plays in the development of the disease. In the present study, we present data on the establishment of a new animal model of diabetic retinopathy that incorporates both hyperglycaemia and inflammation. We hypothesized that inflammation may… CONTINUE READING

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