Intravitreal ganciclovir in the treatment of AIDS-associated cytomegalovirus retinitis.

@article{Ussery1988IntravitrealGI,
  title={Intravitreal ganciclovir in the treatment of AIDS-associated cytomegalovirus retinitis.},
  author={F M Ussery and Simon Gibson and R H Conklin and Dominique Piot and E W Stool and A J Conklin},
  journal={Ophthalmology},
  year={1988},
  volume={95 5},
  pages={640-8}
}
Ganciclovir (BW B759U, DHPG, dihydroxy propoxymethyl guanine) was injected directly into the vitreous in 14 eyes of 11 patients with severe acquired immune deficiency syndrome (AIDS)-associated cytomegalovirus (CMV) retinitis. All 11 patients either demonstrated serious myelosuppression which precluded the continuation of intravenous ganciclovir therapy (5 patients) or were experiencing progressive CMV retinitis despite therapy with maximum-tolerable dosages of intravenous ganciclovir (6… CONTINUE READING