Intraventricular recombinant tissue plasminogen activator for lysis of intraventricular haemorrhage.

  title={Intraventricular recombinant tissue plasminogen activator for lysis of intraventricular haemorrhage.},
  author={Veit Rohde and Carlo Schaller and Werner E. Hassler},
  journal={Journal of neurology, neurosurgery, and psychiatry},
  volume={58 4},
A prospective series of 20 patients with moderate to severe intraventricular haemorrhage (IVH) was studied for the effect of intraventricular administration of recombinant tissue plasminogen activator (rt-PA) on reduction of haematoma volume and prognosis. On the day of haemorrhage ventriculostomy was performed and 2 to 5 mg of rt-PA were injected via the external ventricular drainage, followed by drainage closure for two hours. In 14 patients rt-PA treatment was repeated. Computed tomography… CONTINUE READING


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