Intravenously administered histamine increases choroidal but not retinal blood flow.

  title={Intravenously administered histamine increases choroidal but not retinal blood flow.},
  author={Claudia Zawinka and Hemma Resch and Leopold Schmetterer and Guido T. Dorner and Gerhard Garhofer},
  journal={Investigative ophthalmology & visual science},
  volume={45 7},
PURPOSE To determine the effect of intravenously administered histamine on both retinal and choroidal blood flow in humans. METHODS A randomized, double-masked, two-way crossover study was performed in 14 healthy volunteers. Placebo or histamine was administered intravenously in stepwise increasing doses (0.08 microg/kg/min, 0.16 microg/kg/min, and 0.32 microg/kg/min). Retinal vessel diameters were measured with a retinal vessel analyzer, and retinal venous blood speed was assessed by bi… CONTINUE READING
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