Intravenous treatment of autoimmune hemolytic anemia with very high dose gammaglobulin.

@article{Bussel1986IntravenousTO,
  title={Intravenous treatment of autoimmune hemolytic anemia with very high dose gammaglobulin.},
  author={James B Bussel and Charlotte Cunningham-Rundles and C{\'e}cile Abraham},
  journal={Vox sanguinis},
  year={1986},
  volume={51 4},
  pages={264-9}
}
Autoimmune hemolytic anemia (AIHA) has been considered to be unresponsive to intravenous gammaglobulin (IVGG) at the doses that are effective in immune thrombocytopenic purpura and autoimmune neutropenia (usually 2 g/kg total dose). This study reports the use of a higher dose (5 g/kg total dose over 5 days) in four severe cases of AIHA which resulted in a sustained remission in two patients, a transient response in the third, and a failure in the forth patient. These data suggest that larger… CONTINUE READING

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