Intravenous peramivir for treatment of influenza in hospitalized patients.

  title={Intravenous peramivir for treatment of influenza in hospitalized patients.},
  author={Michael G Ison and Joseph Fraiz and Barry N Heller and Luis Jauregui and Graham Mills and William D. O'Riordan and Brian O'Neil and Elliott Geoffrey Playford and J. Douglass Rolf and Eduardo Sada-D{\'i}az and Jenna Elder and Phil Collis and J. Esteban Hern{\'a}ndez and W P Sheridan},
  journal={Antiviral therapy},
  volume={19 4},
BACKGROUND Influenza causes over 200,000 hospitalizations a year in the United States, but few antiviral treatment studies have focused on patients hospitalized with influenza. This open-label, randomized study was initiated during the 2009 H1N1 pandemic to help assess the antiviral activity, safety and tolerability of 5-10 days treatment with two different dosing regimens of the intravenous neuraminidase inhibitor, peramivir, in hospitalized subjects with influenza. METHODS Quantitative… CONTINUE READING
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