Intravenous magnesium sulfate for the treatment of acute asthma in the emergency department.

@article{Skobeloff1989IntravenousMS,
  title={Intravenous magnesium sulfate for the treatment of acute asthma in the emergency department.},
  author={Emil Skobeloff and W H Spivey and Robert M. McNamara and Lee Greenspon},
  journal={JAMA},
  year={1989},
  volume={262 9},
  pages={1210-3}
}
Conventional nebulized beta-agonist therapy has met with disappointing results in an increasing number of moderate to severe asthmatics who may be characterized as "poor responders." Thirty-eight patients suffering from acute exacerbations of moderate to severe asthma were treated in an emergency department with an intravenous infusion of saline placebo or 1.2 g of magnesium sulfate after conventional beta-agonist therapy failed to produce significant improvement in peak expiratory flow rate… CONTINUE READING