Intravenous magnesium reduces infarct size after ischemia/reperfusion injury combined with a thrombogenic lesion in the left anterior descending artery.

@article{Ravn1999IntravenousMR,
  title={Intravenous magnesium reduces infarct size after ischemia/reperfusion injury combined with a thrombogenic lesion in the left anterior descending artery.},
  author={H B Ravn and U Moeldrup and Carl Brookes and L B Ilkjaer and Philip White and Melvin Chew and Lynn E. Jensen and S. Johnsen and L Birk-Soerensen and V E Hjortdal},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={1999},
  volume={19 3},
  pages={569-74}
}
Experimental studies have demonstrated that intravenous magnesium (Mg) can protect the ischemic myocardium and has an antithrombotic effect. In patients with myocardial infarction, the reperfusion injury is complicated by the presence of a thrombogenic area in the affected coronary artery that may cause repetitive thrombus formation and embolization. We investigated the effect of Mg on infarct size in a randomized study in pigs. Myocardial infarction was induced by a 50-minute mechanical… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 21 references

Magnesium reduces free radicals in an in vivo occlusion-reperfusion model.Circulation

  • AG Lawrence, RS Smith, SC Dejong, SM Martin, GR Beuttner, RE. Kerber
  • 1997

Similar Papers

Loading similar papers…