Intravenous lidocaine for effective pain relief after bimaxillary surgery

  title={Intravenous lidocaine for effective pain relief after bimaxillary surgery},
  author={Uilyong Lee and Young-Jun Choi and Geun Joo Choi and Hyun Kang},
  journal={Clinical Oral Investigations},
ObjectivesThe aim of this prospective, randomized, double-blind, placebo-controlled study was to evaluate the analgesic effect of intravenous lidocaine on postoperative pain in bimaxillary surgery.Materials and methodsBetween July 2015 and November 2015, 52 consecutive patients that underwent bimaxillary surgery were recruited to the present study. The patients were randomly divided into two groups: group L (1.5 mg/kg bolus and 2 mg/kg/h continuous infusion during the operation) and group C… 
Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults.
The effects (benefits and risks) of perioperative intravenous (IV) lidocaine infusion compared to placebo/no treatment or compared to epidural analgesia on postoperative pain and recovery in adults undergoing various surgical procedures are assessed.
Effect of Intravenous Lidocaine Infusion on Postoperative Early Recovery Quality in Upper Airway Surgery
The aim of this randomized, double‐blinded, controlled trial was to investigate the effect of perioperative lidocaine infusion on postoperative early recovery quality in upper airway surgery.
Pain Medicine in Oral and Maxillofacial Surgery
A significant amount of empirical progress has been made in the management of pain over the last century,largely as a result of the introduction of a more effective pharmacological agent and the
Management of postoperative pain in maxillofacial surgery.
The evidence base for postoperative analgesia after maxillofacial surgery is described and the implications of poorly managed pain, risk factors for the development of severe pain, and pharmacological and non-pharmacological analgesic strategies to manage it are discussed.
Lidocaine attenuates lipopolysaccharide-induced inflammatory responses and protects against endotoxemia in mice by suppressing HIF1α-induced glycolysis.
Lidocaine can be used as a potential therapeutic agent for sepsis because it dose-dependently inhibits lipopolysaccharide (LPS)-induced production of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) in macrophages and that lidocaine protects mice from LPS-induced inflammation.


Intravenous Lidocaine for Effective Pain Relief after Inguinal Herniorrhaphy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study
  • H. Kang, B. Kim
  • Medicine
    The Journal of international medical research
  • 2011
It is concluded that intravenous lidocaine injection reduced post-operative pain after inguinal herniorrhaphy, is easy to administer and may have potential to become routine practice for this type of surgery.
Preemptive effects of a combination of preoperative diclofenac, butorphanol, and lidocaine on postoperative pain management following orthognathic surgery.
Preemptive multimodal analgesia was not observed in this study and POPI in the PACU was significantly lower in group P than in group C, whereas there were no significant differences at FWI, 24, 48, and 72 hours after extubation in both groups.
Intraoperative systemic infusion of lidocaine reduces postoperative pain after lumbar surgery: a double-blinded, randomized, placebo-controlled clinical trial.
  • K. Kim, Dae-Chul Cho, +4 authors G. Choi
  • Medicine
    The spine journal : official journal of the North American Spine Society
  • 2014
Intraoperative systemic infusion of lidocaine decreases pain perception during microdiscectomy, thus reducing the consumption of opioid and the severity of postoperative pain, and contributes to reduce the length of HS.
A comparison of patient-controlled and fixed schedule analgesia after orthognathic surgery.
In patients undergoing orthognathic surgery, the naproxen and PCA regimens provided better analgesia than the codeine regimen.
Effect of intraoperative intravenous lidocaine on postoperative pain and return of bowel function after laparoscopic abdominal gynecologic procedures.
These study results are consistent with previous research suggesting that intraoperative lidocaine infusion may improve postoperative pain levels and may shorten the time to return of bowel function.
Preoperative diclofenac sodium and tramadol for pain relief after bimaxillary osteotomy.
Preoperative diclofenac or tramadol, compared with placebo, effectively decreases postoperative opioid consumption via intravenous patient-controlled analgesia.
Postoperative analgesia in orthognathic surgery patients: diclofenac sodium or paracetamol?
A single dose of diclofenac or paracetamol effectively decreases the intensity of postoperative pain after bimaxillary osteotomy.
Intraperitoneal and intravenous lidocaine for effective pain relief after laparoscopic appendectomy: a prospective, randomized, double-blind, placebo-controlled study
Intravenous lidocaine injection is as effective as intraperitoneal instillation for reducing pain and fentanyl consumption and lidocaine intravenous administration is a better alternative for reducing the pain of patients who are undergoing laparoscopic surgery.
Systemic Lidocaine to Improve Postoperative Quality of Recovery After Ambulatory Laparoscopic Surgery
Systemic lidocaine improves postoperative quality of recovery in patients undergoing outpatient laparoscopy, and is a safe, inexpensive, effective strategy to improvequality of recovery after ambulatory surgery.
Experimental incision-induced pain in human skin: effects of systemic lidocaine on flare formation and hyperalgesia
The findings suggest that pre‐traumatic treatment with lidocaine reduces the excessive inputs from the injured peripheral nerves, thus suppressing development of flare formation and secondary hyperalgesia through peripheral and central mechanisms, respectively.